Participant
1: Kings College London
St John’s Institute of Dermatology, Division of Genetics and
Molecular Medicine, King’s College School of Medicine, King’s
College London (KCL), London, United Kingdom
Description of organization:
St
John’s Institute of Dermatology is the most important skin
research organization in the UK and has an international reputation
as a centre of expertise for basic and clinical dermatology
research. It is based in new state-of-the art laboratories at
Guy’s Hospital, London. St John’s is part of King’s
College London, which is ranked in the top 25 universities
in the world (Times Higher 2007).
The main tasks allocated:
Responsible for the management and communication of the consortium.
Will also study: (i) the relationship between DNA photodamage
in the skin and the urine in close cooperation with Partner
5 and (ii) the role of the erythema action spectrum as a spectral
model for the immunosuppressive effects of ultra-violet radiation
(UVR) in close cooperation with partner 3 and (iii) assess the
spectral relationship between erythema (skin redness) and vitamin
D synthesis.
Contact: Professor Antony Young
ICEPURE Principal Coordinator
Please note all email addresses have been
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Participant 2: Bispebjerg
Hospital
Department of Dermatology, Bispebjerg Hospital (BBH), Copenhagen
University, Copenhagen, Denmark
Description of organization:
Bispebjerg
Hospital's Department of Dermatology is the main dermatology
centre in Denmark and with more than 85,000 patients per year
it also makes it the largest dermatology centre in Northern
Europe. The department comprises a research section with 22
MDs, pharmacists, engineers, biologists and laboratory technicians.
The department has a high level of expertise in photobiology,
photomedicine and skin cancer.
The main tasks allocated:
Participant 2 has the largest role in the consortium and will
be responsible for the development and provision of the electronic
personal dosimeters to the other participants. Participant 2
will have overall responsibility for the population UVR exposure
studies and the analysis of the UVR exposure data from these
studies.
Contact: Professor Hans Christian Wulf
Work Package 2 Leader: Dr Jakob Heydenreich
Work Package 3 Leader: Dr Elisabeth Thieden
Participant 3: Medical
University of Lodz
Department of Dermatology, Medical University of Lodz (MUL),
Lodz, Poland
Description of organization:
The Medical University of
Lodz is one of the largest medical schools in Poland with
more than 1100 academic teachers. The Department of Dermatology
has wide experience in research work, especially in the field
of alterations of skin immunity by environmental factors, autoimmune
skin diseases such as pemphigus, systemic lupus erythematosus
and systemic scleroderma. A major area of research and therapy
is the treatment of skin diseases provoked by UVR. The department
has a well-equipped photobiology unit.
The main tasks allocated:
Participant 3 will perform studies within WP3
and WP5. In particular
these will be the population UVR exposure studies in Poland,
in close collaboration with Participant 2, in which the effect
of UVR exposure on immunity will be determined. Participant
4 will collect urine from the volunteers in these studies for
the assessment of DNA damage.
Contact: Dr Joanna Narbutt
Participant 4: Karolinska
Institutet
Department of Biosciences and Nutrition, Karolinska Institutet
(KI), Huddinge, Sweden
Description of organization:
The Karolinska Institutet (KI) is
ranked as the top research institute in Sweden and is very highly
regarded from an international perspective as well. It is well
known for selecting the Nobel Prize winner in medicine every
year.
The main tasks allocated:
The Karolinska Institutet will be responsible for the assessment
of DNA photodamage in the urine taken from the volunteers in
the population studies. It will also work with Partner 1 to
determine the relationship between DNA photodamage in the skin
and in the urine.
Contact: Dr
Dan Segerbäck
Publications related to project: http://cebp.aacrjournals.org/cgi/content/abstract/14/12/2868
Participant 5:
Centre for Research in Environmental Epidemiology
Centre for Research in Environmental Epidemiology (CREAL) at
Institut Municipal d'Investigació Mèdica (IMIM),
Barcelona, Spain
Description of organization:
The Centre for Research in Environmental
Epidemiology (CREAL), founded in 2006, is a joint initiative
of the Government of Catalonia, the Institut Municipal d´Investigació
Mèdica (IMIM-IMAS) and the Universitat Pompeu Fabra (UPF).
CREAL, under the leadership of Josep Maria Anto and with over
60 staff, is a leader in environmental exposure assessment and
epidemiological research and is based in a new research park,
Parc de Recerca Biomèdica
de Barcelona.
The main tasks allocated:
CREAL will lead WP7 which
will result in a systematic literature review of the relationship
between UVR exposure and different health outcomes. In addition,
this work package will integrate the UVR exposure, biomarker
and modelling data generated from WP 3-6 so that it can be incorporated
into the systematic review. CREAL will also supply logistical
support for the UVR population studies in Spain, done by Partner
2 (BBH) in WP3.
Contact: Dr Mark J Nieuwenhuijsen
Participant 6: University
of Veterinary Medicine (UVM) Vienna
Institute of Medical Physics and Biostatistics, University of
Veterinary Medicine (UVM) Vienna, Austria
Description of organization:
The Institute
of Medical Physics and Biostatistics is part of the University
of Veterinary Medicine, which was founded in 1765. The institute’s
main tasks are research and the education of students in medical-physics,
bio-physics, statistics and epidemiological modelling. Courses
in radiation protection are also given.
The main tasks allocated:
Contribution to WP3 (responsible
for the personal dosimetry of farmer families and in a snow
environment in Austria), WP4
(contribute to the collection of ozone layer data from satellite
and of UVR ground data) and WP6
(contribution to the development and refinement of modelling
UVR on inclined planes and personal exposure).
Contact: Dr Alois Schmalwieser
Participant 7: Health
Protection Agency
Health Protection Agency (HPA), Centre for Radiation, Chemical
and Environmental Hazards, Chilton, Didcot, OX11 0RQ, United
Kingdom
Description of organization:
The Health Protection Agency
(HPA), founded in 2003, is a non-departmental public body, incorporating
the National Radiological
Protection Board (NRPB) in 2005. The HPA has a network of
about 3000 staff based at three major centres (Colindale, Porton
and Chilton): the Centre for Radiation, Chemical and Environmental
Hazards is based at Chilton.
The main tasks allocated:
HPA will participate in WP 4 on Satellite and Ground Station
Data and will make ground station measurements of incident solar
UVR and assist in the health assessments made in WP 7.
Contact: Dr John B O’Hagan
Participant 8: Danish
Meteorological Institute
The Danish Meteorological Institute (DMI), Copenhagen, Denmark
Description of organization:
The DMI is the national
meteorological service for Denmark, Greenland and the Faeroe
Islands, with extensive research interests, e.g., in climate
variability on monthly to centennial time scales. The Danish
Climate Centre, a research division of the DMI, has extensive
experience in climate modelling. Both state-of-the-art atmospheric
global circulation models (GCMs) are installed and running on
DMI’s supercomputer as is the regional climate model HIRHAM,
developed jointly by the DMI and the Max Planck Institute for
Meteorology. A new and improved version of HIRHAM facilitates
a horizontal resolution of down to 10 km and the installation
of a new supercomputer in 2008 will boost computational speed
and make high-resolution simulations feasible.
The main tasks allocated:
The DMI is responsible for WP6
that comprises implementing a UVR radiative model into the HIRHAM
regional climate model to facilitate projections of the influence
of future climate on personal UVR exposure. The UVR model will
be developed to handle exposure on non-static surfaces and account
for behavioural and cultural aspects of the exposure of different
populations groups assessed in WP 3. The DMI will also lead
on WP4, in very close collaboration
with participants 6 and 7.
Contact: Paul Eriksen
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